Take the Quiz
Guide · Updated 2026-05-25

Semaglutide and Cardiovascular Health

Released: Last reviewed:

Semaglutide is the first GLP-1 with an FDA-approved CV indication for non-diabetic patients. SELECT trial: 20% MACE reduction in non-diabetic adults with overweight/obesity + CVD.

EducationalUpdated 2026-05-25
Researched By
Dr. Parmis
Medical Researcher · Western University of Health Sciences
Medically Reviewed By
Dr. Jonathan Snipes, MD · Kim Callender, NP (FNP-BC)
Last medically reviewed: October 15, 2026 · This page is informational and does not constitute medical advice.

Overview

Semaglutide is the first GLP-1 with an FDA-approved CV indication for non-diabetic patients. SELECT trial: 20% MACE reduction in non-diabetic adults with overweight/obesity + CVD.

Related guides